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TREATMENT DIAGNOSIS BMS CAUSES SIGNS AND SYMPTOMS Source: U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Dental and Craniofacial Research dry or sore mouth. bitter or metallic changes in taste tingling or numbness on the tip of the tongue or in the mouth Anxiety and depression Moderate to severe burning in the mouth anxiety and depression. poorly-fitting dentures or allergies to denture materials acid reflux oral candidiasis, a fungal infection in the mouth nutritional deficiencies dry mouth, which can be caused by many medicines and disorders such as Sjo¨gren’s syndrome or diabetes hormonal changes damage to nerves that control pain and taste allergy testing for denture materials, certain foods, or other substances that may be causing your symptoms. oral swab to check for oral candidiasis blood work to look for infection, nutritional deficiencies, and disorders associated with BMS such as diabetes or thyroid problems medications switching medicine, where possible, if a drug you are taking is causing your burning mouth recommending supplements for nutritional deficiencies treating existing disorders such as diabetes, Sjo¨gren’s syndrome, or a thyroid problem to improve burning mouth symptoms adjusting or replacing irritating dentures Burning Mouth Syndrome (BMS)