Characteristics of Selected Frontotemporal Dementias

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Corticobasal Degeneration
Supranuclear Palsy
Characteristics of Selected Frontotemporal Dementias
FTDP-17
Pick’s
Disease
difficulties in thinking, concentrating, paying attention; gradual emotional apathy, loss of moral judgment; generalized dementia
language problems: use of wrong words, echoing what others say, mutism can develop
personality and behavioral changes: disinhibition, inappropriate social behaviors, loss of mental flexibility and empathy; development of obsessive-compulsive behaviors, compulsive overeating, food cravings, putting any object in mouth
cognitive decline: word finding difficulties, other language difficulties though comprehension remains preserved; executive functions, attention, and abstract reasoning become impaired; mutism eventually develops
psychiatric symptoms: delusions, visual or auditory hallucinations
behavioral changes: loss of initiative, disinhibition, obsessive-compulsive behavior, restlessness, verbal aggressiveness
personality/behavioral changes: apathy, increased irritability, angry outbursts, depression, progressive dementia
motor difficulties: problems with balance and gait; problems controlling eye movement, involuntary closing of the eyes, inability to maintain eye contact with others; difficulties with swallowing
difficulty swallowing
sudden contractions of muscles or muscle groups
hesitant and halting speech
cognitive and visual-spatial impairments, loss of ability to make familiar and purposeful movements
signs of parkinsonism: poor coordination, rigidity, impaired balance
Source: U.S. National Institute of Health, National Institute of Aging. www.nia.nih.gov