Coagulation

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Coagulation
Illustration of process of coagulation in three steps showing adherence of platelets to wound site and eventual clot.
Endothelium
Collagen
Platelets immediately form a haemostatic plug at the site of injury.
Collagen in the blood vessel endothelium activates platelets that adhere to wound site.
Activated platelets then release the contents of their granules, which contain a variety of substances that stimulate further platelet activation and enhance the haemostatic process.
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