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Maintenance The laminar airflow hood shall be certified annually by an independent contractor. The independent contractor will certify that the LAFW or barrier isolator is functioning correctly and meets the air quality requirement of ISO Class 5. Are the sterile compounding areas used for high risk, preparations? Air sampling will be performed in areas most prone to contamination during compounding activities. The laminar airflow hood shall have routine contract maintenance performed every six (6) months, or when the LAFW is relocated, to assure proper function to HEPA filters. Documentation of such maintenance will be maintained in the Pharmacy Department. The laminar airflow hood shall be cleaned every shift and PRN with disinfectant solution. All surfaces should be cleaned adequately. Non-shedding cloths used to clean hood surfaces shall be discarded after use. Pre-filters will be changed monthly or more frequently if necessary due to working conditions. A log will be maintained documenting when the filters are changed. The laminar airflow hood shall be turned on continuously except for filter changes and other required maintenance. YES Air quality sampling will be completed weekly, at a minimum, for sterile compounding areas used for high-risk preparations. NO Air quality sampling will be completed once a month, at a minimum, for sterile compounding areas used for low- and medium-risk preparations.